Ketamine for Treatment-Resistant Depression: What You Need to Know

Depression affects millions of people worldwide, and while traditional treatments help many, approximately one-third don’t respond adequately to standard antidepressants and therapy (Rush et al., 2006). For these individuals, ketamine represents an additional option in the treatment toolkit. This guide explains both ketamine treatment alone and the enhanced approach of ketamine-assisted psychotherapy (KAP), including realistic expectations about benefits and limitations.